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Covid will be cured in five days; Israel with miracle inhalers

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For many patients with severe infections of the novel coronavirus, it is not the virus itself that kills them but the series of events it triggers. One of the most fatal outcomes is when patients develop Acute respiratory distress syndrome (ARDS) with cytokine storms.

Cytokines are protein groups that coordinate the immune response. In severe cases of COVID-19 and even pneumonia, a “cytokine storm” can take place, where a positive feedback loop creates an immune response so strong it damages critical bodily functions.

It has been hypothesised for years that targeted interventions on the cytokine storm itself could help with cases of severe pnemonia. Now, Israeli scientists have applied this to treatment of COVID-19 itself, with a result that Prime Minister Benjamin Netanyahu himself has dubbed a “miracle drug”.

The EXO-CD24 inhaler treatment, developed by Prof Nadir Arber at the Tel Aviv Sourasky Medical Center (Ichilov Hospital), was tested on 30 patients with moderate to severe condition, all of whom recovered—29 within just 3-5 days.

It is administered through inhalation, once a day, in a procedure that takes only a few minutes, for five days, Arber told the Jewish News Syndicate.

“It is based on exosomes that the body is releasing from the cell membrane and uses for intercellular communication. We enrich the exosomes with the 24CD protein, which is known to play an important role in regulating the immune system,” said Arber’s director of laboratory Dr. Shiran Shapira, who has studied the CD24 protein for decades.

The medicine will now move on to additional trial phases, though the hospital sees it as a potential game-changer.

The treatment has attracted such attention that Greek Prime Minister Kyriakos Mitsotakis discussed it with Netanyahu during his recent visit. Netanyahu kept a vial of it in his pocket, revealing it after his meeting with Mitsotakis, and dubbed it a “miracle drug”.

“If you’re infected by corona and are seriously ill and have a lung problem, take this, inhale it, and you come out feeling good,” he said.

Prof. Ronni Gamzu, Israel’s former coronavirus Czar, hailed the treatment as “innovative and sophisticated” and said that the results of the Phase I trial “give us all an expression of confidence in the method.”

Mitsotakis expressed Greece’s willingness to participate in clinical trials.

“Assuming that we can overcome the regulatory hurdles, Greece would be happy to participate in clinical trials,” he said, adding “We would all be very relieved if we could find a drug that could cure the disease itself.”

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ഭൂകമ്പം ഫിജിയെ പിടിച്ചുകുലുക്കി, റിക്ടർ സ്കെയിലിൽ 6.0 രേഖപ്പെടുത്തിയ ഭൂചലനം

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സുവ: ദ്വീപ് രാജ്യമായ ഫിജിയിൽ ഭൂചലനം. റിക്ടർ സ്‌കെയിലിൽ 6.0 തീവ്രത രേഖപ്പെടുത്തിയ ഭൂചലനത്തിൽ നാശനഷ്ടങ്ങൾ ഉണ്ടായതായി റിപ്പോർട്ടില്ല. 398 കിലോമീറ്റർ ആഴത്തിൽ പ്രകമ്പനം അനുഭവപ്പെട്ടതായി യുഎസ് ഭൗമശാസ്ത്ര കേന്ദ്രം അറിയിച്ചു. ലെവൂക്ക നഗരത്തിന് 340 കിലോമീറ്റർ കിഴക്ക് മാറിയായിരുന്നു പ്രകമ്പനം. പ്രാദേശിക സമയം രാവിലെ 11.35 ഓടെയായിരുന്നു ഭൂചലനം അനുഭവപ്പെട്ടത്. സുനാമി മുന്നറിയിപ്പുകളൊന്നും നൽകിയിട്ടില്ലെന്ന് അധികൃതർ അറിയിച്ചു. ഭൂചലനം ഉണ്ടായ വിവരം ജർമ്മൻ ജിയോസയൻസ് റിസർച്ച് സെന്ററും സ്ഥിരീകരിച്ചിട്ടുണ്ട്.

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Archaeologists discover rare 2,000-y-o oil lamp in Jerusalem’s City of David on Pilgrimage Road

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The Israel Antiquities Authority announced the discovery of a rare oil lamp, with its wick still preserved, from under the foundation of a building erected on Jerusalem’s famed Pilgrimage Road soon after the destruction of the Second Temple almost 2,000 years ago.

The IAA researchers believe the bronze lamp, shaped like a grotesque face cut in half and estimated to be from the late first century or the early second century CE, was put in the foundation of the building in Jerusalem’s City of David for good fortune, The Times of Israel reported.

“This half of a lamp, and in fact half a face, which was discovered in the City of David, is a very rare object, with only a few discovered in the whole world, and is the first of its kind to be discovered in Jerusalem,” Yuval Baruch of the IAA was quoted as saying.

“It is possible that the importance of the building, and the need to bless its activity with luck by burying a foundation deposit, was due to its proximity to the Siloam Pool, which was also used in the Roman period as the central source of water within the city,” IAA archaeologist Ari Levy told The Jerusalem Post.

Speaking to Haaretz, Levy explained, “Foundation deposits, in general, go back to the dim reaches of antiquity. It was accepted in construction in general, to bring luck and symbolic defense of the building — and to cast fear and awe on attackers. Its significance was highly symbolic, not functional.”

Haaretz said the lamp featured a goaty male half-face complete with (half a) satyr’s beard and a horned forehead.

Only one other such lamp has ever been found in an archaeological context — and that was in Budapest, according to Levy.

Experts believe that Pilgrimage Road, where the building had been erected, is the path ancient Jews walked to reach the Temple Mount three times a year — in the festivals of Passover, Shavuot and Sukkot.

“The street was built during the period of Governor Pontius Pilates,” Levy said. “It was inaugurated around the year 30 CE and it was used for about 40 years until the Temple was destroyed in 70 CE.”

Baruch added: “Decorated bronze oil lamps were discovered throughout the Roman Empire. For the most part, such oil lamps stood on stylish candelabras or were hung on a chain. Collections around the world contain thousands of these bronze lamps, many of which were made in intricate shapes, indicating the artistic freedom that Roman metal artists possessed.”
Sources:Christian Post

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